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Learn more about medium borosilicate glass bottles

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Learn more about medium borosilicate glass bottles

“Pharmaceutical glass is a packaging material that comes into direct contact with medicines. It occupies a large proportion in the field of pharmaceutical packaging materials and has irreplaceable properties and advantages. ”

Pharmaceutical glass is mainly used in the packaging of medicines such as powder injections, freeze dryers, blood products, oral solutions, etc., where the dosage is. The larger ones are injections and oral solutions. Compared with other packaging materials such as plastic and metal, medicinal glass has better properties and stability and has more advantages in price.

Depending on the production process and use, medicinal glass is mainly divided into molded bottles and controlled bottles. Molded bottles use molds to make liquid glass into medicine bottles, while controlled bottles use flame thermal processing and molding equipment to make glass tubes into pharmaceutical packaging bottles of fixed shape and volume. Controlled bottles have the advantages of thin walls and light weight, but there are many production processes and higher prices.

According to the different materials, the performance is ranked from low to high. Pharmaceutical glass can be divided into soda-lime glass, low borosilicate glass, medium borosilicate glass, and high borosilicate glass. The main difference lies in the different water resistance. Due to the special nature of the new crown vaccine, the packaging material standard requires medium borosilicate glass. The United States, Europe and other countries have made it mandatory for all injectable preparations and biological preparations to use medium borosilicate glass packaging.

Migration between glass components and drugs is the main reason for the reduced efficacy or even ineffectiveness of drugs. It is reported that glass water resistance refers to the amount of alkali precipitated per unit mass of glass under specific conditions. The smaller the amount of alkali precipitated by glass, the higher the water resistance grade, and the smaller the impact on aqueous drugs.

However, unlike domestic vaccines, which are at the forefront, domestic medium borosilicate glass is slightly behind.